Pairwise alignment
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- Pairwise alignmentsearch for term
In the first step, two sequences are padded by gaps so that they are the same length and so that they display the maximum similarity on a residue to residue basis. An optimal Pairwise Alignment is an alignment which has the maximum amount of similarity with the minimum number of residue 'substitutions'. (http://www.netsci.org/Science/Bioinform/terms.html)