Padlock-probe amplification
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- Padlock-probe amplification search for term
A ligation-mediated bimolecular assay for a target sequence in which the two query oligonuceotides (5' and 3' sequences) are derived from the two ends of a contiguous oligonucleotide. Ligation of the two ends creates a circular structure that is intertwined with the target sequence. (Fan 2006)